The Yankees, meanwhile, are playing through a four-game winning streak, which is tied for their longest of the year. New York has scored at least six runs in three straight games, and it will match veteran Hiroki Kuroda up against rookie left-hander Tommy Milone in the series finale.
Kuroda has lost three of his last four starts, and he's notched a 5.82 ERA and allowed six home runs in that span. Half of that output came in an 8-1 loss to Toronto, and Kuroda is 0-4 on the road this year. The 37-year-old had only three no-decisions in 32 starts last year with the Dodgers.
Milone, acquired from Washington as part of the offseason trade for Gio Gonzalez, has gone 4-0 with a 0.60 ERA in his first four starts at Oakland's O.co Coliseum. The 25-year-old southpaw has struck out (32) more than twice as many batters as he's walked (14) through his first nine starts for the A's.
Oakland's bullpen allowed three late runs in Saturday's 9-2 rout, but it's pitched pretty well over the life of the team's skid. The A's relief staff has worked 13 1/3 innings in the last four games and has pitched to a 2.63 ERA over that span. Now, Oakland will need that same effort to keep runs off the board.
"I've been a part of some good bullpens here," reliever Jerry Blevins said. "And we always seem to have a really good bullpen, but I've never been part of one where every single member of the bullpen is pretty much a lights-out pitcher. You've got guys that'll step in in any particular situation, and they're going to put up zeros. When one of our relievers gives up a run, it's like a shock, like, 'Oh wow, he's human.' I've never been a part of something like that."
Yankees: Cano climbs over .300 mark
Robinson Cano pushed his average to .302 and drilled his third homer in four games on Saturday, continuing a surge that has gone on for more than three weeks. Cano has hit safely in 19 of his last 23 games and has seen his batting average raised more than 45 points (from .255) since May 2.
Cano went 3-for-5 in Saturday's victory, notching a home run and a double. New York's second baseman leads the American League with 17 doubles this season, and since making his big league debut in 2005, he has more doubles (303) than any other Major League hitter.
A's: Injuries take toll on lineup
The A's have seven players on the disabled list, and they fielded a starting lineup Saturday that featured four players batting under the Mendoza Line (.200). Oakland went into Saturday's game with the lowest batting average (.210) among all big league teams.
Outfielder Josh Reddick -- batting .271 with 13 homers -- went deep Saturday has been one of the team's only consistent offensive threats. Yoenis Cespedes, sidelined by a hand injury, is batting .245 with five home runs and could be back in the lineup by the end of next week.
Derek Jeter's next hit will push him past Hall of Famer George Brett (3,154) for sole possession of 14th place on the all-time hit list.
The Yankees have won 12 of their last 13 games in Oakland, and they haven't lost on the road against the A's since April 2010.
Oakland is 11-12 in May and has had a winning record in this month in just two of the previous seven seasons.