TORONTO -- The A's on Tuesday were again without speedster Coco Crisp, who was held out of the lineup for a second straight game because of a strained right calf that could potentially sideline him for the entire Toronto series.

Crisp remained mum on the topic, but manager Bob Melvin expressed a dose of hope regarding his center fielder.

"Coco is having some issues with it," the skipper said. "When he came in today, I probably would've said he wouldn't be available for the series, but after the treatment he had today, I'm encouraged that maybe he could play here at some point."

Crisp stole a career-high four bases on Saturday in Tampa Bay before the injury forced his departure in the ninth. He's garnered 10 stolen bases in his last seven games and is also batting .348 with eight multi-hit games over his last 17 contests.

With Crisp out of the mix, Cliff Pennington was slotted into the second spot of the lineup, where he's hitting just .213 this year, and Ryan Sweeney received a start in center field while batting eighth.

Worth noting

• Lefty Craig Breslow, who turned 31 on Monday, was available for Tuesday's series opener in Toronto after being held out of action Sunday because of a knot in his left shoulder.

• Manager Bob Melvin said the tentative plan is to not play Hideki Matsui on the outfield turf in Toronto but, rather, have him in the designated hitter's spot all three days.

• Closer Andrew Bailey is a perfect 28-for-28 in save opportunities after the All-Star break in his career.