Teams 
| Club Records -- Batting | Opponent | Date |
|---|---|---|
| Most runs -- 24 | Detroit | May 18, 1912 |
| Boston | May 1, 1929 | |
| Most hits, nine innings -- 29 | Boston | May 1, 1929 |
| Most hits, extra innings -- 29 (15 innings) | Texas | July 1, 1979 |
| Most triples -- 6 | Detroit | May 18, 1912 |
| Most home runs -- 8 | California | June, 27 1996 |
| Most home runs, inning -- 4 | Boston | August, 21 1997 |
| Tampa Bay | August, 1 1999 | |
| Chicago | April 27, 2002 | |
| Most total bases -- 44 | California | June 27, 1996 |
| Boston | May 1, 1929 | |
| Most strikeouts -- 19 | Seattle | June 24, 1997 |
| Individual Records -- Batting | Player(s) | Opponent | Date |
|---|---|---|---|
| Most runs -- 5 | Norm Siebern | Indians | May May 62 |
| Michael Edwards | Texas | September 8, 1978 | |
| Mark McGwire | Indians | June 27, 1987 | |
| Luis Polonia | Kansas City | September 9, 1988 | |
| Most hits -- 6 | Danny Murphy | -- | July 8, 2002 |
| Jimmie Foxx | -- | May 30, 1930 | |
| Roger Cramer | -- | June 20, 1932 | |
| Jimmie Foxx | -- | July 10, 1932 | |
| Bob Johnson | -- | June 16, 1934 | |
| Roger Cramer | -- | July 13, 1935 | |
| Joe DeMaestri | -- | July 8, 1955 | |
| Most singles -- 6 | Roger Cramer | -- | June 20, 1932 |
| Most doubles -- 4 | Frankie Hayes | -- | July 25, 1936 |
| Most triples -- 3 | Bert Campaneris | Cleveland | August 29, 1967 |
| Most home runs -- 3 (25 times) | Last: Erubiel Durazo | Baltimore | August 18, 1904 |
| Most RBIs -- 10 | Reggie Jackson | Boston | June 14, 1969 |
| Most total bases -- 16 | Jimmie Foxx | -- | July, 10 1932 |
| Most walks -- 5 (several times) | Last: Mark McGwire | Kansas City | April 26, 1997 |
| Most strikeouts -- 5 (several times) | Last: Nick Swisher | San Diego | June 29, 2006 |
| Most sacrifice flies -- 2 (Several times) | Last: Nick Swisher | Seattle | September 12, 2007 |
| Most stolen bases -- 6 | Eddie Collins | -- | September 11, 1912 |
| Eddie Collins | -- | September 22, 1912 |
| Club Records -- Pitching | Opponent | Date |
|---|---|---|
| Most runs allowed -- 29 | Chicago | May 23, 1955 |
| Most walks allowed -- 18 | Detroit | May 9, 1916 |
| Most home runs allowed -- 8 | New York | June 28, 1939 |
| Most wild pitches -- 4 (several times) | Last: Anaheim | September 24, 1998 |
| Most balks -- 5 | Seattle | April 13, 1988 |
| Individual Records -- Pitching | Player(s) | Opponent | Date |
|---|---|---|---|
| Most innings pitched -- 24 | Jack Coombs | Boston | September 1, 1906 |
| Most hits allowed, nine innings -- 26 | Hod Lisenbee | -- | September 11, 1936 |
| Most hits allowed, extra-innings -- 29 | Eddie Rommel | -- | July 10, 1932 |
| Most walks allowed -- 16 | Bruno Haas | -- | June 13, 1915 |
| Most strikeouts, nine innings -- 16 | Jose Rijo | Seattle | April 19, 1986 |
| Most strikeouts, extra-innings -- 18 | Jack Coombs | Boston | September 1, 1906 |
| Most strikeouts, inning -- 4 | Erik Hiljus | Texas | June 30, 2001 |
| Blake Stein | Tampa Bay | July, 27 1998 | |
| Most home runs allowed -- 6 | George Caster | -- | September 24, 1940 |
